Effects of Saccharides from Arctium lappa L. Root on FeCl3-Induced Arterial Thrombosis via the ERK/NF-κB Signaling Pathway

The Myosin II Inhibitor, Blebbistatin, Ameliorates FeCl3-induced Arterial Thrombosis via the GSK3β-NF-κB Pathway

Arterial thrombosis and its related diseases are major healthcare problems worldwide. Blebbistatin is an inhibitor of myosin II, which plays an important role in thrombosis. The aim of our study is to explore the effect and potential mechanism of blebbistatin on arterial thrombosis. A ferric chloride (FeCl3) solution at a concentration of 5% was used to induce carotid artery thrombosis in mice....

Protective effects of Arctium lappa L. root extracts (AREs) on high fat diet induced quail atherosclerosis

BACKGROUND This study was designed to evaluate the protective effects of Arctium lappa L. root extracts (AREs) from different extraction methods (aqueous, ethanol, chloroform and flavone) on atherosclerosis. METHODS Quails (Coturnix coturnix) were subjected to high fat diet, with or without one of the four different AREs or positive control simvastatin. Blood samples were collected before tre...

Protective effects of Arctium lappa L . root extracts ( AREs ) on high fat diet induced 1 quail atherosclerosis

The Essential oil Composition of Arctium lappa Root and Leaf

Using plants and natural products as medicine is increasing every day. The reason might be a tendency that the societies mostly have toward natural and original products especially natural drugs. Essential oilsare referred to aromatic composition which is found in different parts of a plant and can be used for different remedial and hygienic purposes. One of the plants which have been used a lo...

Anti-allergic and anti-inflammatory effects of butanol extract from Arctium Lappa L

BACKGROUND Atopic dermatitis is a chronic, allergic inflammatory skin disease that is accompanied by markedly increased levels of inflammatory cells, including eosinophils, mast cells, and T cells. Arctium lappa L. is a traditional medicine in Asia. This study examined whether a butanol extract of A. lappa (ALBE) had previously unreported anti-allergic or anti-inflammatory effects. METHODS Th...